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产品信息
PA5-105259
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PSMC5(Accession P62195), corresponding to amino acid residues K94-P144.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853864
产品详细信息
Antibody detects endogenous levels of total PSMC5.
靶标信息
Human SUG1 (also known as p45, Rpt6 and Cim3) is a component of the 19S regulatory subunit of the 26S proteosome complex. It is one of the AAA ATPas found in the 19S regulatory complex that is thought to participate in the unfolding of ubiquitinated proteins in an ATP-dependent manner. It has also been shown to directly interact with the nucleotide excision repair protein XPB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 26S protease regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; 26S proteasome regulatory subunit 8; for proteasomal ATPase (SUG1); mSUG1; MSUG1 protein; p45/SUG; peptidase (prosome, macropain) 26S subunit, ATPase 5; protease (prosome, macropain) 26S subunit, ATPase 5; proteasomal ATPase (SUG1); proteasome (prosome, macropain) 26S subunit, ATPase, 5; proteasome 26S ATPase subunit 5; Proteasome 26S subunit ATPase 5; proteasome p45/SUG; Proteasome subunit p45; Tat-binding protein homolog 10; testicular tissue protein Li 149; thy; Thyroid hormone receptor-interacting protein 1; thyroid receptor interactor 1; TRIP1
基因别名: mSUG1; p45; p45/SUG; PSMC5; S8; SUG-1; SUG1; TBP10; TRIP1
UniProt ID: (Human) P62195, (Mouse) P62196, (Rat) P62198
Entrez Gene ID: (Human) 5705, (Mouse) 19184, (Rat) 81827
MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
transcription from RNA polymerase II promoter
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
negative regulation of programmed cell death
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of inclusion body assembly
positive regulation of canonical Wnt signaling pathway
positive regulation of proteasomal protein catabolic process
protein catabolic process
