Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
H00005724-B01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PTAFR (ACE87813.1, 1 a.a. approximately 342 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Tissue lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEPHDSSHMD SEFRYTLFPI VYSIIFVLGV IANGYVLWVF ARLYPCKKFN EIKIFMVNLT MADMLFLITL PLWIVYYQNQ GNWILPKFLC NVAGCLFFIN TYCSVAFLGV ITYNRFQAVT RPIKTAQANT RKRGISLSLV IWVAIVGAAS YFLILDSTNT VPDSAGSGNV TRCFEHYEKG SVPVLIIHIF IVFSFFLVFL IILFCNLVII RTLLMQPVQQ QRNAEVKRRA LWMVCTVLAV FIICFVPHHV VQLPWTLAEL GFQDSKFHQA INDAHQVTLC LLSTNCVLDP VIYCFLTKKF RKHLTEKFYS MRSSRKCSRA TTDTVTEVVV PFNQIPGNSL KN
靶标信息
PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: PAF receptor; PAF-R; Platelet-activating factor receptor
基因别名: PAFR; PTAFR
UniProt ID: (Human) P25105, (Mouse) Q62035
Entrez Gene ID: (Human) 5724, (Mouse) 19204
lipopolysaccharide binding
lipopolysaccharide receptor activity
G-protein coupled receptor activity
platelet activating factor receptor activity
phospholipid binding
G-protein coupled purinergic nucleotide receptor activity
mitogen-activated protein kinase binding
signal transducer activity
G-protein coupled receptor
cytokine production
regulation of transcription from RNA polymerase II promoter
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
parturition
response to symbiotic bacterium
positive regulation of phospholipase C activity
lipopolysaccharide-mediated signaling pathway
positive regulation of tumor necrosis factor production
inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
positive regulation of neutrophil degranulation
transcytosis
positive regulation of interleukin-6 biosynthetic process
positive regulation of translation
negative regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of vasodilation
phosphatidylinositol-mediated signaling
positive regulation of smooth muscle cell proliferation
interferon-gamma-mediated signaling pathway
positive regulation of inositol phosphate biosynthetic process
cellular response to gravity
cellular response to cAMP
cellular response to fatty acid
response to dexamethasone
positive regulation of voltage-gated chloride channel activity
positive regulation of leukocyte tethering or rolling
positive regulation of sensory perception of pain
positive regulation of transcytosis
positive regulation of maternal process involved in parturition
positive regulation of gastro-intestinal system smooth muscle contraction
cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
pattern recognition receptor signaling pathway
signal transduction
response to lipopolysaccharide
