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产品信息
PA5-18776
产品规格
种属反应
Zebrafish
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (QTGSKKEPFNYSQ) corresponding to the internal amino acids of ptc1 (aa 896-906).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10987555
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: etID309849.2; FLJ26746; FLJ42602; HGNC:9585; leprechaun; OTTHUMP00000021709; OTTHUMP00000021710; patched; patched 2; patched1; ptc-1; PTCH protein -3; RP11-435O5.3
基因别名: lep; ptc1; ptc2
Entrez Gene ID: (Zebrafish) 30189
