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PTF1A Antibody (PA5-81247) in WB
Western Blot using PTF1A Polyclonal Antibody (Product # PA5-81247) at 1:500 dilution. Lane A: Jurakt Whole Cell Lysate, Lane B: MCF-7 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 35 kDa. Observed band size: 45 kDa.
产品信息
PA5-81247
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the C-terminus of the Human PTF1A
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2788472
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human PTF1A.
靶标信息
PFT1A is a component of the pancreas transcription factor 1 complex and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLH transcription factor p48; bHLHa29; Class A basic helix-loop-helix protein 29; class II bHLH protein PTF1A; exocrine pancreas-specific transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; Pancreas transcription factor 1 subunit alpha; Pancreas-specific transcription factor 1a; PTF1-p48
基因别名: BHLHA29; PACA; PAGEN2; PTF1-p48; PTF1A; PTF1P48
UniProt ID: (Human) Q7RTS3
Entrez Gene ID: (Human) 256297
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
embryo development
tissue development
retina layer formation
cerebellum development
pancreas development
exocrine pancreas development
amacrine cell differentiation
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
neuron fate commitment
regulation of neural retina development
