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PTGES Antibody (PA5-116872) in IHC (P)
Immunohistochemistry analysis of PTGES in paraffin-embedded mouse testis. Samples were incubated with PTGES Polyclonal antibody (Product # PA5-116872) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116872
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTGES (NP_0048691)
偶联物
形式
Liquid
浓度
0.39 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901503
产品详细信息
Positive Samples: MCF7, Mouse lung, Rat lung
Immunogen sequence: MPAHSLVMSS PALPAFLLCS TLLVIKMYVV AIITGQVRLR KKAFANPEDA LRHGGPQYCR SDPDVERCLR AHRNDMETIY PFLFLGFVYS FLGPNPFVAW
靶标信息
PTGES is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glutathione peroxidase PTGES; glutathione S-transferase 1-like 1; Glutathione transferase PTGES; Inducible prostaglandin E synthase; MGST1-L1; MGST1-like 1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; Prostaglandin E synthase; tumor protein p53 inducible protein 12
基因别名: 2410099E23Rik; D2Ertd369e; MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; MPGES1; PGES; PIG12; PP102; PP1294; PTGES; TP53I12
UniProt ID: (Human) O14684, (Rat) Q9JHF3, (Mouse) Q9JM51
Entrez Gene ID: (Human) 9536, (Rat) 59103, (Mouse) 64292
prostaglandin biosynthetic process
acute inflammatory response
chronic inflammatory response
prostaglandin metabolic process
signal transduction
negative regulation of cell proliferation
response to organic cyclic compound
cyclooxygenase pathway
response to lipopolysaccharide
response to retinoic acid
response to cytokine
response to calcium ion
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
