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产品信息
PA5-33001
产品规格
种属反应
Bovine,
Dog,
Chicken,
Horse,
Human,
Non-human primate,
Pig,
Rabbit,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 14 amino acid peptide from near N-terminus of human PTGES.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550462
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat, Bovine, Dog, Elephant, Panda, Rabbit, Horse, Pig, Opossum, Turkey, Chicken, Platypus, Pufferfish, Zebrafish, Stickleback (100%); Mouse, Xenopus, Pike (93%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
PTGES is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glutathione peroxidase PTGES; glutathione S-transferase 1-like 1; Glutathione transferase PTGES; Inducible prostaglandin E synthase; MGST1-L1; MGST1-like 1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; Prostaglandin E synthase; tumor protein p53 inducible protein 12
基因别名: MGST-IV; MGST1-L1; MGST1L1; MPGES; MPGES-1; MPGES1; PGES; PIG12; PP102; PP1294; PTGES; TP53I12; zgc:110052
UniProt ID: (Bovine) Q95L14, (Human) O14684, (Dog) A0SYQ0, (Horse) Q8HZJ2, (Rat) Q9JHF3
prostaglandin biosynthetic process
negative regulation of cell proliferation
cellular response to interleukin-1
acute inflammatory response
chronic inflammatory response
prostaglandin metabolic process
signal transduction
response to organic cyclic compound
cyclooxygenase pathway
response to lipopolysaccharide
response to retinoic acid
response to cytokine
response to calcium ion
cell migration involved in gastrulation
oxidation-reduction process
