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PTGIR Antibody (PA5-75406) in WB
Western blot analysis of PTGIR in Lane 1: HEK293T whole cell lysate (40 µg), Lane 2: PC3 whole cell lysate (40 µg), Lane 3: SGC7901 whole cell lysate (40 µg), Lane 4: PC12 whole cell lysate (40 µg), Lane 5: 3T3-L1 whole cell lysate (40 µg). Samples were incubated with PTGIR polyclonal antibody (Product # PA5-75406) at a dilution of 1:500.
产品信息
PA5-75406
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 200-250 of Human PTGIR.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719134
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IP receptor; PGI receptor; PGI2 receptor; Prostacyclin receptor; Prostaglandin I2 receptor; Prostanoid IP receptor
基因别名: IP; PRIPR; PTGIR
UniProt ID: (Human) P43119
Entrez Gene ID: (Human) 5739
inflammatory response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of cAMP biosynthetic process
response to lipopolysaccharide
positive regulation of GTPase activity
positive regulation of cAMP-mediated signaling
negative regulation of smooth muscle cell proliferation
cellular response to prostaglandin D stimulus
