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Peptide sequence: VRTKTWTLKK HFVGYPTNSD FELKTSELPP LKNGEVLLEA LFLTVDPYMR
Sequence homology: Cow: 93%; Guinea Pig: 83%; Horse: 83%; Human: 93%; Rabbit: 83%; Rat: 79%
PTGR1 encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 15-oxoprostaglandin 13-reductase; D3T-inducible gene 1 protein; Dithiolethione-inducible gene 1 protein; FLJ99229; Leukotriene B4 12-hydroxydehydrogenase; MGC34943; NAD(P)H-dependent alkenal/one oxidoreductase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PRG-1; Prostaglandin reductase 1; zinc binding alcohol dehydrogenase domain containing 3
基因别名: LTB4DH; PGR1; PTGR1; ZADH3
UniProt ID: (Human) Q14914
Entrez Gene ID: (Human) 22949