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产品信息
H00005764-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E7
抗原
PTN (NP_002816, 45 a.a. approximately 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: SDCGEWQWSV CVPTSGDCGL GTREGTRTGA ECKQTMKTQR CKIPCNWKKQ FGAECKYQFQ AWGECDLNTA LKTRTGSLKR ALHNAECQKT VTISKPCGKL TKPKPQAESK
靶标信息
Pleiotrophin (PTN) is an 18 kDa secreted heparin and chondroitin-binding protein that is a regulatory cytokine critical to the early development of blood vessels and neurons. High PTN serum levels are associated with a variety of solid tumors. It was shown that patients with multiple myeloma (MM) also have elevated serum levels of this protein. The expression of this protein is very limited in normal adult tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HB-GAM; HBBM; HBGF-8; HBNF; HBNF-1; heparin affin regulatory protein; Heparin-binding brain mitogen; Heparin-binding growth factor 8; Heparin-binding growth-associated molecule; heparin-binding neurite outgrowth promoting factor; Heparin-binding neurite outgrowth-promoting factor; Heparin-binding neurite outgrowth-promoting factor 1; OSF-1; Osteoblast-specific factor 1; Pleiotrophin; pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1); PTN
基因别名: HARP; HB-GAM; HBBM; HBGF-8; HBGF8; HBNF; HBNF-1; HBNF1; NEGF1; OSF-1; PTN
UniProt ID: (Human) P21246
Entrez Gene ID: (Human) 5764
liver development
transmembrane receptor protein tyrosine phosphatase signaling pathway
nervous system development
heart development
learning
positive regulation of cell proliferation
regulation of cell shape
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
response to activity
negative regulation of angiogenesis
spinal cord development
cerebellum development
thalamus development
bone mineralization
lung development
negative regulation of cell migration
response to estradiol
response to progesterone
cellular response to UV
cellular response to platelet-derived growth factor stimulus
response to drug
positive regulation of apoptotic process
negative regulation of catalytic activity
estrous cycle
endothelial cell differentiation
negative regulation of membrane potential
negative regulation of epithelial cell proliferation
positive regulation of cell division
retinal rod cell differentiation
negative regulation of glial cell proliferation
long-term synaptic potentiation
cellular response to vitamin D
cellular response to hypoxia
negative regulation of mesenchymal cell proliferation
response to kainic acid
rod bipolar cell differentiation
response to ciliary neurotrophic factor
positive regulation of skeletal muscle acetylcholine-gated channel clustering
negative regulation of neuromuscular junction development
response to nerve growth factor
positive regulation of hepatocyte proliferation
