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产品信息
PA5-120349
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human PTP4A2 (NP_536316.1).
偶联物
形式
Liquid
浓度
2.13 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2913921
产品详细信息
Positive test controls include: MCF7, Mouse skeletal muscle, Mouse brain, Mouse kidney, Mouse liver, Rat brain. The target is usually found in the following locations: Cell membrane, Cytoplasm, Early endosome.
Immunogen sequence: FTEELKKYGV TTLVRVCDAT YDKAPVEKEG IHVLDWPFDD GAPPPNQIVD DWLNLLKTKF REEPGCCVAV H
靶标信息
PRL-2, also known as Protein tyrosine phosphatase 4a2 (Ptp4a2) is a unique nuclear protein tyrosine phosphatase (PTP) that plays a central role in regulating diverse cellular processes. PRL-1 is induced in mitogen-stimulated cells and regenerating liver. PRL-2 exhibits 87% identity to PRL-1 in their amino acid sequences. All mouse PRL proteins contain a C-terminal consensus sequence for prenylation. All PRL proteins bear significant sequence homology to Cdc14p and the tumor suppressor PTEN/MMAC1. PRL-2 is preferentially expressed in skeletal muscle. PRL-2 is also expressed at lower levels in other tissues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HU-PP-1; OV-1; phosphatase of regenerating liver 2; PRL-2; protein tyrosine phosphatase 4a2; protein tyrosine phosphatase IVA; protein tyrosine phosphatase IVA2; Protein tyrosine phosphatase type IVA 2; Protein-tyrosine phosphatase 4a2; Protein-tyrosine phosphatase of regenerating liver 2; PTP(CAAXII); tyrosine-phosphatase
基因别名: BM-008; HH13; HH7-2; HU-PP-1; OV-1; PRL-2; PRL2; ptp-IV1a; ptp-IV1b; PTP4A; PTP4A2; PTPCAAX2
UniProt ID: (Human) Q12974, (Rat) Q6P9X4, (Mouse) O70274
Entrez Gene ID: (Human) 8073, (Rat) 85237, (Mouse) 19244
