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PTPN23 Antibody (H00025930-B01P) in WB
Western Blot analysis of PTPN23 expression in transfected 293T cell line (H00025930-T02) by PTPN23 MaxPab polyclonal antibody.
Lane 1: PTPN23 transfected lysate(63.47 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PTPN23 transfected lysate(63.47 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00025930-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PTPN23 (AAH04881, 1 a.a. approximately 577 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MGPQAAPLTI RGPSSAGQST PSPHLVPSPA PSPGPGPVPP RPPAAEPPPC LRRGAAAADL LSSSPESQHG GTQSPGGGQP LLQPTKVDAA EGRRPQALRL IERDPYEHPE RLRQLQQELE AFRGQLGDVG ALDTVWRELQ DAQEHDARGR SIAIARCYSL KNRHQDVMPY DSNRVVLRSG KDDYINASCV EGLSPYCPPL VATQAPLPGT AADFWLMVHE QKVSVIVMLV SEAEMEKQKV ARYFPTERGQ PMVHGALSLA LSSVRSTETH VERVLSLQFR DQSLKRSLVH LHFPTWPELG LPDSPSNLLR FIQEVHAHYL HQRPLHTPII VHCSSGVGRT GAFALLYAAV QEVEAGNGIP ELPQLVRRMR QQRKHMLQEK LHLRFCYEAV VRHVEQVLQR HGVPPPCKPL ASASISQKNH LPQDSQDLVL GGDVPISSIQ ATIAKLSIRP PGGLESPVAS LPGPAEPPGL PPASLPESTP IPSSSPPPLS SPLPEAPQPK EEPPVPEAPS SGPPSSSLEL LASLTPEAFS LDSSLRGKQR MSKHNFLQAH NGQGLRATRP SDDPLSLLDP LWTLNKT
靶标信息
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HD-PTP; His domain-containing protein tyrosine phosphatase; Protein tyrosine phosphatase TD14; PTP-TD14; Tyrosine-protein phosphatase non-receptor type 23
基因别名: HD-PTP; HDPTP; KIAA1471; PTP-TD14; PTPN23
UniProt ID: (Human) Q9H3S7
Entrez Gene ID: (Human) 25930
negative regulation of epithelial cell migration
protein transport
peptidyl-tyrosine dephosphorylation
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
cilium morphogenesis
positive regulation of homophilic cell adhesion
positive regulation of adherens junction organization
positive regulation of early endosome to late endosome transport
