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Product Details
PA5-56964
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PTPRO. Recombinant protein control fragment (Product #RP-101062).
Conjugate
Form
Liquid
Concentration
0.11 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2646135
Product Specific Information
Immunogen sequence: TRVNISYWEG KDFRTMLYKD FFKGKTVFNH WLPGMCYSNI TFQLVSEATF NKSTLVEYSG VSHEPKQHRT APYPPQNISV RIVNLNKNNW EEQSGNFPEE SFMRSQDTIG KEKLFHFTEE TPEIPSGNIS SGWP
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.
Target Information
Glomerular epithelial protein 1 (GLEPP1), also designated protein tyrosine phosphatase U2 (PTPase U2) or receptor-type tyrosine-protein phosphatase O (PTPRO), belongs to the protein-tyrosine phosphatase family. GLEPP1 is a Type I membrane protein containing 8 fibronectin type-III domains and 1 tyrosine-protein phosphatase domain. GLEPP1 is expressed primarily in the glomeruli of the kidney, but is also detected in placenta, lung and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FMI; Glomerular epithelial protein 1; hPTP-J; osteoclastic transmembrane protein-tyrosine phosphatase; PCP-2; PCP2; phosphotyrosine phosphatase U2; protein tyrosine phosphatase PTP-U2; Protein tyrosine phosphatase U2; protein tyrosine phosphatase, receptor type, O; PTP phi; PTP pi; PTP-J; PTP-RO; PTP-U2; PTPase U2; PTPRU; R-PTP-O; R-PTP-psi; R-PTP-U; Receptor-type tyrosine-protein phosphatase O
Gene Aliases: GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPRO; PTPROT; PTPU2; R-PTP-O
UniProt ID: (Human) Q16827
Entrez Gene ID: (Human) 5800
cell morphogenesis
monocyte chemotaxis
regulation of glomerular filtration
negative regulation of glomerular filtration
protein dephosphorylation
axon guidance
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
lamellipodium assembly
glomerulus development
peptidyl-tyrosine dephosphorylation
slit diaphragm assembly
glomerular visceral epithelial cell differentiation
negative regulation of canonical Wnt signaling pathway
negative regulation of retinal ganglion cell axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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