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产品信息
H00005800-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3F4
抗原
PTPRO (AAH35960, 1 a.a. approximately 597 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MGHLPTGIHG ARRLLPLLWL FVLFKNATAF HVTVQDDNNI VVSLEASDVI SPASVYVVKI TGESKNYFFE FEEFNSTLPP PVIFKASYHG LYYIITLVVV NGNVVTKPSR SITVLTKPLP VTSVSIYDYK PSPETGVLFE IHYPEKYNVF TRVNISYWEG KDFRTMLYKD FFKGKTVFNH WLPGMCYSNI TFQLVSEATF NKSTLVEYSG VSHEPKQHRT APYPPQNISV RIVNLNKNNW EEQSGNFPEE SFMRSQDTIG KEKLFHFTEE TPEIPSGNIS SGWPDFNSSD YETTSQPYWW DSASAAPESE DEFVSVLPME YENNSTLSET EKSTSGSFSF FPVQMILTWL PPKPPTAFDG FHIHIEREEN FTEYLMVDEE AHEFVAELKE PGKYKLSVTT FSSSGSCETR KSQSAKSLSF YISPSGEWIE ELTEKPQHVS VHVLSSTTAL MSWTSSQENY NSTIVSVVSL TCQKQKESQR LEKQYCTQVN SSKPIIENLV PGAQYQVVIY LRKGPLIGPP SDPVTFAIVP TGIKDLMLYP LGPTAVVLSW TRPYLGVFRK YVVEMFYFNP ATMTSEWTTY YEIAATVSLT ASVVIFP
靶标信息
Glomerular epithelial protein 1 (GLEPP1), also designated protein tyrosine phosphatase U2 (PTPase U2) or receptor-type tyrosine-protein phosphatase O (PTPRO), belongs to the protein-tyrosine phosphatase family. GLEPP1 is a Type I membrane protein containing 8 fibronectin type-III domains and 1 tyrosine-protein phosphatase domain. GLEPP1 is expressed primarily in the glomeruli of the kidney, but is also detected in placenta, lung and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FMI; Glomerular epithelial protein 1; hPTP-J; osteoclastic transmembrane protein-tyrosine phosphatase; PCP-2; PCP2; phosphotyrosine phosphatase U2; protein tyrosine phosphatase PTP-U2; Protein tyrosine phosphatase U2; protein tyrosine phosphatase, receptor type, O; PTP phi; PTP pi; PTP-J; PTP-RO; PTP-U2; PTPase U2; PTPRU; R-PTP-O; R-PTP-psi; R-PTP-U; Receptor-type tyrosine-protein phosphatase O
基因别名: GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPRO; PTPROT; PTPU2; R-PTP-O
UniProt ID: (Human) Q16827
Entrez Gene ID: (Human) 5800
cell morphogenesis
monocyte chemotaxis
regulation of glomerular filtration
negative regulation of glomerular filtration
protein dephosphorylation
axon guidance
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
lamellipodium assembly
glomerulus development
peptidyl-tyrosine dephosphorylation
slit diaphragm assembly
glomerular visceral epithelial cell differentiation
negative regulation of canonical Wnt signaling pathway
negative regulation of retinal ganglion cell axon guidance
