Invitrogen

PTPRZ Polyclonal Antibody

5 Published Figures

3 References

View all (7) PTPRZ antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)
Published Figures (5)

FIGURE: 1 / 7

PTPRZ Antibody (PA5-101832) in WB

Western blot analysis of PTPRZ in HUVEC cell lysate (Lane 1: treated with blocking peptide). Samples were incubated with PTPRZ polyclonal antibody (Product # PA5-101832).

PTPRZ Antibody in Western Blot, Immunohistochemistry (Paraffin) (WB, IHC (P))

Product Image Gallery

Product Details

PA5-101832

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human PTPRZ1(Accession P23471), corresponding to amino acid residues F121-K171.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

AB_2851264

Product Specific Information

Antibody detects endogenous levels of total PTPRZ1.

Target Information

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D.

Nature protocols

van Ineveld RL,Collot R,Román MB,Pagliaro A,Bessler N,Ariese HCR,Kleinnijenhuis M,Kool M,Alieva M,Chuva de Sousa Lopes SM,Wehrens EJ,Rios AC

PA5-101832 was used in Immunohistochemistry, Immunocytochemistry, Western Blot to provide a one-week protocol for eight-fluorescent-marker 3D visualization and exploration of intact tissue of various origins at single-cell resolution.

Thu Dec 01 00:00:00 UTC 2022

TMAO Aggregates Neurological Damage Following Ischemic Stroke by Promoting Reactive Astrocytosis and Glial Scar Formation via the Smurf2/ALK5 Axis.

Frontiers in cellular neuroscience

Su H,Fan S,Zhang L,Qi H

PA5-101832 was used in Western Blot, Immunohistochemistry (Paraffin) to identify the evolutionarily TMAO/Smurf2/ALK5 signaling as a major genetic factor in the control of reactive astrocyte proliferation and glial scar formation in ischemic stroke, thus laying a theoretical foundation for the identification of ischemic stroke.

Tue Apr 06 00:00:00 UTC 2021

TMAO Aggregates Neurological Damage Following Ischemic Stroke by Promoting Reactive Astrocytosis and Glial Scar Formation via the Smurf2/ALK5 Axis.

Frontiers in cellular neuroscience

Su H,Fan S,Zhang L,Qi H

Tue Apr 06 00:00:00 UTC 2021

TMAO Aggregates Neurological Damage Following Ischemic Stroke by Promoting Reactive Astrocytosis and Glial Scar Formation via the Smurf2/ALK5 Axis.

Frontiers in cellular neuroscience

Su H,Fan S,Zhang L,Qi H

Tue Apr 06 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; 6B4 proteoglycan; Phosphacan; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1; protein tyrosine phosphate, receptor type, Z; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; PTP zeta; R-PTP-zeta; R-PTP-zeta-2; receptor-type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta

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Gene Aliases: AI850339; DSD-1-PG; HPTPZ; HPTPzeta; HTPZP2; phosphacan; PTP-ZETA; PTP18; PTPbeta; PTPRZ; PTPRZ1; PTPRZ2; PTPZ; PTPzeta; PTPzeta-A; PTPzeta-B; PTPzeta-S; R-PTP-zeta-2; RPTPB; RPTPbeta; RPTPz

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UniProt ID: (Human) P23471, (Mouse) B9EKR1, (Rat) Q62656

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Entrez Gene ID: (Human) 5803, (Mouse) 19283, (Rat) 25613

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Function(s)

protein tyrosine phosphatase activity transmembrane receptor protein tyrosine phosphatase activity protein binding fibroblast growth factor binding phosphoprotein phosphatase activity hydrolase activity phosphatase activity protein phosphatase protein modifying enzyme

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PTPRZ Polyclonal Antibody

PTPRZ Antibody (PA5-101832) in WB

Product Details

PA5-101832

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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