Invitrogen

PTPRZ Polyclonal Antibody

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PTPRZ Antibody (PA5-101832) in WB

Western blot analysis of PTPRZ in HUVEC cell lysate (Lane 1: treated with blocking peptide). Samples were incubated with PTPRZ polyclonal antibody (Product # PA5-101832).

PTPRZ Antibody in Western Blot, Immunohistochemistry (Paraffin) (WB, IHC (P))

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产品信息

PA5-101832

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

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免疫细胞化学 (ICC/IF)

1:100-1:500

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human PTPRZ1(Accession P23471), corresponding to amino acid residues F121-K171.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2851264

产品详细信息

Antibody detects endogenous levels of total PTPRZ1.

靶标信息

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D.

Nature protocols

van Ineveld RL,Collot R,Román MB,Pagliaro A,Bessler N,Ariese HCR,Kleinnijenhuis M,Kool M,Alieva M,Chuva de Sousa Lopes SM,Wehrens EJ,Rios AC

PA5-101832 was used in Immunohistochemistry, Immunocytochemistry, Western Blot to provide a one-week protocol for eight-fluorescent-marker 3D visualization and exploration of intact tissue of various origins at single-cell resolution.

Thu Dec 01 00:00:00 UTC 2022

TMAO Aggregates Neurological Damage Following Ischemic Stroke by Promoting Reactive Astrocytosis and Glial Scar Formation via the Smurf2/ALK5 Axis.

Frontiers in cellular neuroscience

Su H,Fan S,Zhang L,Qi H

PA5-101832 was used in Western Blot, Immunohistochemistry (Paraffin) to identify the evolutionarily TMAO/Smurf2/ALK5 signaling as a major genetic factor in the control of reactive astrocyte proliferation and glial scar formation in ischemic stroke, thus laying a theoretical foundation for the identification of ischemic stroke.

Tue Apr 06 00:00:00 UTC 2021

TMAO Aggregates Neurological Damage Following Ischemic Stroke by Promoting Reactive Astrocytosis and Glial Scar Formation via the Smurf2/ALK5 Axis.

Frontiers in cellular neuroscience

Su H,Fan S,Zhang L,Qi H

Tue Apr 06 00:00:00 UTC 2021

TMAO Aggregates Neurological Damage Following Ischemic Stroke by Promoting Reactive Astrocytosis and Glial Scar Formation via the Smurf2/ALK5 Axis.

Frontiers in cellular neuroscience

Su H,Fan S,Zhang L,Qi H

Tue Apr 06 00:00:00 UTC 2021

生物信息学

蛋白别名: 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; 6B4 proteoglycan; Phosphacan; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1; protein tyrosine phosphate, receptor type, Z; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; PTP zeta; R-PTP-zeta; R-PTP-zeta-2; receptor-type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta

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基因别名: AI850339; DSD-1-PG; HPTPZ; HPTPzeta; HTPZP2; phosphacan; PTP-ZETA; PTP18; PTPbeta; PTPRZ; PTPRZ1; PTPRZ2; PTPZ; PTPzeta; PTPzeta-A; PTPzeta-B; PTPzeta-S; R-PTP-zeta-2; RPTPB; RPTPbeta; RPTPz

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UniProt ID: (Human) P23471, (Mouse) B9EKR1, (Rat) Q62656

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Entrez Gene ID: (Human) 5803, (Mouse) 19283, (Rat) 25613

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功能

protein tyrosine phosphatase activity transmembrane receptor protein tyrosine phosphatase activity protein binding fibroblast growth factor binding phosphoprotein phosphatase activity hydrolase activity phosphatase activity protein phosphatase protein modifying enzyme

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