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产品信息
PA5-53280
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.30 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2646139
产品详细信息
Immunogen sequence: LFRHLHTVSQ ILPQVTSATE SDKVPLHASL PVAGGDLLLE PSLAQYSDVL STTHAASETL EFGSESGVLY KTLMFSQVEP PSSDAMMHAR SSGPEPSYAL SDNEGSQHIF TVSYSSAIPV HDSVGVTYQG SLFSGPSHIP IPKSSLIT
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 72%.
靶标信息
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein tyrosine phosphatase, receptor-type, Z polypeptide 1; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta; R-PTP-zeta-2; receptor-type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta
基因别名: HPTPZ; HPTPzeta; HTPZP2; phosphacan; PTP-ZETA; PTP18; PTPRZ; PTPRZ1; PTPRZ2; PTPZ; R-PTP-zeta-2; RPTPB; RPTPbeta
UniProt ID: (Human) P23471
Entrez Gene ID: (Human) 5803
hematopoietic progenitor cell differentiation
protein dephosphorylation
axonogenesis
axonal fasciculation
central nervous system development
learning or memory
negative regulation of cell proliferation
visual learning
negative regulation of cell-substrate adhesion
hippocampus development
peptidyl-tyrosine dephosphorylation
positive regulation of fibroblast proliferation
oligodendrocyte differentiation
regulation of dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
regulation of oligodendrocyte progenitor proliferation
positive regulation of dendrite development
positive regulation of Schwann cell migration
positive regulation of neuron death
negative regulation of dendrite development
positive regulation of neuron migration
