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Product Details
PA5-68838
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide corresponding to a region of mouse PUS1 (aa 51-100).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2689407
Product Specific Information
This target displays homology in the following species: Mouse: 100%; Rat: 100%
Target Information
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Pseudouridylate synthase 1 homolog; tRNA pseudouridine synthase 1; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA-uridine isomerase I
Gene Aliases: A730013B20Rik; MNCb-0873; MPUS1; mPus1p; Pus1
UniProt ID: (Mouse) Q9WU56
Entrez Gene ID: (Mouse) 56361
RNA binding
protein binding
pseudouridine synthase activity
isomerase activity
ligand-dependent nuclear receptor transcription coactivator activity
pivalyl-CoA mutase activity
o-hydroxylaminobenzoate mutase activity
lupeol synthase activity
beta-amyrin synthase activity
poly(A) RNA binding
baruol synthase activity
lyase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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