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Product Details
PA5-85285
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PUS1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792428
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (93%), Sheep (87%).
Positive Control: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mitochondrial tRNA pseudouridine synthase A; Pseudouridylate synthase 1 homolog; tRNA pseudouridine synthase 1; tRNA pseudouridine synthase A, mitochondrial; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA uridine isomerase I; tRNA-uridine isomerase I
Gene Aliases: A730013B20Rik; MLASA1; MNCb-0873; MPUS1; mPus1p; PP8985; PUS1
UniProt ID: (Human) Q9Y606, (Mouse) Q9WU56
Entrez Gene ID: (Human) 80324, (Mouse) 56361
pseudouridylate synthase activity
pseudouridine synthase activity
poly(A) RNA binding
RNA binding
protein binding
isomerase activity
ligand-dependent nuclear receptor transcription coactivator activity
pivalyl-CoA mutase activity
o-hydroxylaminobenzoate mutase activity
lupeol synthase activity
beta-amyrin synthase activity
baruol synthase activity
lyase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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