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产品信息
PA5-50738
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human pseudouridylate synthase 10
偶联物
形式
Liquid
浓度
2.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636190
产品详细信息
The antibody detects endogenous levels of total PUS10 protein.
靶标信息
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: coiled-coil domain containing 139; Coiled-coil domain-containing protein 139; Hup10; pseudouridine synthase 10; Psi55 synthase; putative tRNA pseudouridine synthase Pus10; tRNA pseudouridine 55 synthase; tRNA pseudouridine synthase Pus10; tRNA pseudouridylate synthase; tRNA-uridine isomerase
基因别名: 2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; DOBI; PUS10
UniProt ID: (Human) Q3MIT2, (Mouse) Q9D3U0
Entrez Gene ID: (Human) 150962, (Mouse) 74467
