Invitrogen

PUS7 Monoclonal Antibody (OTI4C6)

PUS7 Antibody in Immunocytochemistry (ICC/IF)

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PUS7 Antibody (MA5-25265) in ICC/IF

Immunofluorescent analysis of PUS7 in COS7 cells. Cells were transfected with a plasmid overexpressing PUS7 and probed with a PUS7 monoclonal antibody (Product # MA5-25265).

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产品信息

MA5-25265

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫细胞化学 (ICC/IF)

1:100

流式细胞分析 (Flow)

1:100

产品规格

种属反应

Dog, Human, Non-human primate, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

OTI4C6

抗原

Full length human recombinant protein of PUS7 produced in HEK293T cell

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.6 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 1% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2723535

靶标信息

Pseudouridylate synthase that catalyzes pseudouridylation of RNAs (PubMed:28073919, PubMed:29628141, PubMed:30778726). Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex (PubMed:29628141). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (PubMed:28073919). In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types (PubMed:29628141). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。