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PA1-9582 detects PYY in human, mouse and rat samples.
PA1-9582 has been successfully used in ELISA procedures.
PA1-9582 immunogen is a synthetic peptide corresponding to amino acids 3-18 of human PYY (IKPEAPGEDASPEELN).
Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); Peptide YY; Peptide YY3-36; Peptide YY3-37; prepro-PYY; PYY; PYY II; PYY-1; PYY-2; PYY-I; PYYI; PYYII
基因别名: GHYY; peptide-YY; PYY; PYY-I; PYY1; RATGHYY; Yy
UniProt ID: (Human) P10082, (Rat) P10631, (Mouse) Q9EPS2
Entrez Gene ID: (Human) 5697, (Rat) 287730, (Mouse) 217212