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PYY Antibody (PA5-119894) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of of Peptide YY in SW620 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 10% negative goat serum for 15 minutes at room temperature. Cells were probed with PYY Polyclonal Antibody (Product # PA5-119894) at a dilution of 1:200 for 1 hour at room temperature, washed with PBS. Alexa Fluor 488 Goat anti-Rabbit IgG was used as the secondary antibody at 1:1,000 dilution. The nuclear counter stain is DAPI (blue... View More
产品信息
PA5-119894
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within N-terminal human Peptide YY
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2913466
产品详细信息
Positive Control: Human small intestine tissue lysate, RAW264.7 cell lysate, rat liver tissue lysate, SW620, SiHa.
Subcellular Location: Secreted.
靶标信息
Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); Peptide YY; Peptide YY3-36; Peptide YY3-37; prepro-PYY; PYY; PYY II; PYY-1; PYY-2; PYY-I; PYYI; PYYII
基因别名: GHYY; peptide-YY; PYY; PYY-I; PYY1; RATGHYY; Yy
UniProt ID: (Human) P10082, (Rat) P10631, (Mouse) Q9EPS2
Entrez Gene ID: (Human) 5697, (Rat) 287730, (Mouse) 217212
