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产品信息
PA5-65160
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2664239
产品详细信息
Immunogen sequence: NCSYESMGESN NDHFQHFPPP PPILETSSLE LASKKPSEIQ QVNNPELGLS RAALQMQFNA AERETNGVHP SRGVNGLING KANSNKSLPT P
Highest antigen sequence identity to the following orthologs - mouse 83%, rat 83%.
靶标信息
Palladin is a cytoskeletal protein required for organization of normal actin cytoskeleton. Palladin plays roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. Palladin may function as a scaffolding molecule with the potential to impact both actin polymerization as well as the assembly of existing actin filaments into higher-order arrays. It binds to proteins that bind to either monomeric or filamentous actin. It localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Palladin's different isoforms may have functional differences. It is also involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ22190; FLJ38193; FLJ39139; myoneurin; Palladin; Sarcoma antigen NY-SAR-77; SIH002
基因别名: CGI-151; CGI151; KIAA0992; MYN; PALLD; PNCA1; SIH002
UniProt ID: (Human) Q8WX93
Entrez Gene ID: (Human) 23022
