Invitrogen

Pan-cadherin Recombinant Rabbit Monoclonal Antibody (ST54-01)

Pan-cadherin Antibody in Immunocytochemistry (ICC/IF)

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Pan-cadherin Antibody (MA5-41143) in ICC/IF

Immunofluorescence analysis of Pan-cadherin was performed using 70% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Pan-cadherin Recombinant Rabbit Monoclonal Antibody (ST54-01) (Product # MA5-41143) at 1:50 dilution in 0.1%... View More

Pan-cadherin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Pan-cadherin Antibody in Western Blot (WB)

Pan-cadherin Antibody in Flow Cytometry (Flow)

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产品信息

MA5-41143

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:1,000

免疫细胞化学 (ICC/IF)

1:50-1:200

流式细胞分析 (Flow)

1:50-1:100

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

ST54-01

抗原

Synthetic peptide within C-terminal human CDH2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2898897

靶标信息

Pan Cadherin including CDH1, CDH2, CDH3, CDH4 protein belong to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: ARC-1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); cadherin 3, type 1, P-cadherin (placental); cadherin 4 type 1 R-cadherin (retinal); cadherin 4, type 1, preproprotein; cadherin 4, type 1, R-cadherin (retinal); cadherin e; Cadherin-1; Cadherin-2; Cadherin-3; Cadherin-4; cadherin-E; Cadherin-N; calcium-dependent adhesion protein, epithelial; calcium-dependent adhesion protein, neuronal; calcium-dependent adhesion protein, placental; CAM 120/80; CD324; CD325; CDw325; CDw325 antigen; cell-CAM 120/80; E-Cadherin; E-cadherin 1; Epithelial cadherin; N-cadherin; N-cadherin 1; Neural cadherin; Neural-cadherin; P-cadherin; Pan Cadherin; Placental cadherin; Placental-cadherin; R-CAD; R-cadherin; retina cadherin; Retinal cadherin; RPE-specific cadherin; Uvomorulin

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基因别名: AA960649; AI385538; Arc-1; AW120700; CAD4; Cadp; CD324; CD325; CDH1; CDH2; CDH3; CDH4; Cdh4l; CDHE; CDHN; CDHP; CDw325; E-cad; ECAD; HJMD; L-CAM; LCAM; N-cadherin; NCAD; P-cadherin; PCAD; R-CAD; R-Cadh; R-cadherin; RCAD; Um; UVO