Invitrogen

Pericentrin Polyclonal Antibody

Pericentrin Antibody in Western Blot (WB)

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Pericentrin Antibody (PA5-37295) in WB

Western blot analysis of Pericentrin in Lane 1: HEK293T whole cell lysate, Lane 2: NIH-3T3 whole cell lysate, Lane 3: H9C2 whole cell lysate. Samples were incubated with Pericentrin polyclonal antibody (Product # PA5-37295) at a dilution of 1:500.

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产品信息

PA5-37295

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to residues in human PCNT

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2553999

产品详细信息

This antibody detects endogenous protein at a molecular weight of 76 kDa.

Purity is >95% by SDS-PAGE.

靶标信息

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.

仅用于科研。不用于诊断过程。未经明确授权不得转售。