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Phospho-AS160 (Ser588) Antibody (PA5-97399) in WB
Western blot analysis of Phospho-AS160 (Ser588) in extracts of HeLa cells. Samples were incubated with Phospho-AS160 (Ser588) Polyclonal antibody (Product # PA5-97399) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. HeLa cells were treated by IGF-1 (50 ng/mL) for 30 minutes after serum-starvation overnight. Lysates/proteins: 25 µg per lan... View More
产品信息
PA5-97399
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic phosphorylated peptide around S588 of human TBC1D4 (NP_0556472)
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2809201
产品详细信息
Immunogen sequence: LGSVD; Positive Samples: HeLa; Cellular Location: Cytoplasm
靶标信息
AS160 (TBC1D4) is a GTPase-activiting protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes the insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane. This movement increases glucose uptake. Mutations associated with the gene cause Diabetes mellitus, non-insulin-dependent, 5 (NIDDM5).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Akt substrate of 160 kDa; AS160; DKFZp779C0666; OTTHUMP00000040818; RP11-159J2.1; RP11-159J2.3; TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC Tre-2; TBC1 domain family member 4; TBC1 domain family, member 4
基因别名: 5930406J04Rik; A930035N22; AS160; AV295684; KIAA0603; NIDDM5; RGD1561609; TBC1D4
UniProt ID: (Human) O60343, (Mouse) Q8BYJ6
Entrez Gene ID: (Human) 9882, (Rat) 306117, (Mouse) 210789
