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Phospho-BLNK (Tyr84) Antibody (MA5-37084) in Flow
Flow cytometry of Phospho-BLNK (Tyr84) using Daudi cells. Samples were incubated in monoclonal Phospho-BLNK (Tyr84) antibody (Product # MA5-37084) with a dilution of 0.01 µg/mL. Images correspond with the following conditions: negative control (light blue), untreated (red), with IFNa/IL-4/pervanadate (green), untreated and blocked with phospho-peptide (black), treated and blocked with phospho peptide (gold)... View More
产品信息
MA5-37084
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
BLNKY84-H4
抗原
A synthetic phospho-peptide corresponding to residues surrounding Tyr84 of human phospho BLNK.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897018
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B cell adaptor containing SH2 domain; B cell linker protein; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; Cytoplasmic adapter protein; MGC111051; SLP-65; Src homology 2 domain-containing leukocyte protein of 65 kDa; Src homology [SH2] domain-containing leukocyte protein of 65 kD
基因别名: AGM4; BASH; bca; BLNK; BLNK-S; LY57; SLP-65; SLP65
UniProt ID: (Human) Q8WV28
Entrez Gene ID: (Human) 29760
