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Phospho-C/EBP beta (Thr188, Thr235) Antibody (PA5-36629) in IHC (P)
Immunohistochemistry analysis of Phospho-C/EBP beta (Thr188, Thr235) in paraffin-embedded human breast carcinoma tissue. Samples were incubated with Phospho-C/EBP beta (Thr188, Thr235) polyclonal antibody (Product # PA5-36629) at a dilution of 1:100.
产品信息
PA5-36629
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide derived from human C/EBP-beta around the phosphorylation site of Threonine 235
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553624
产品详细信息
This antibody detects endogenous levels of human LAP only when phosphorylated at Thr235, mouse and rat LAP only when phosphorylated at Thr188, and LIP only when phosphorylated at Thr37 (molecular weight of 19, 36 and 38 kDa).
Purity is >95% by SDS-PAGE.
靶标信息
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C EBP; C/EBP beta; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; interleukin 6-dependent DNA-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Nuclear factor NF-IL6; nuclear factor of interleukin 6; OTTMUSP00000017503; TCF-5; Transcription factor 5; transcription factor C/EBP beta
基因别名: C/EBP-beta; CEBPB; IL6DBP; NF-IL6; PP9092; TCF5
UniProt ID: (Human) P17676
Entrez Gene ID: (Human) 1051
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
kinase binding
histone acetyltransferase binding
glucocorticoid receptor binding
protein homodimerization activity
histone deacetylase binding
ubiquitin-like protein ligase binding
protein heterodimerization activity
basic leucine zipper transcription factor
ovarian follicle development
embryonic placenta development
granuloma formation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
acute-phase response
inflammatory response
immune response
memory
neuron differentiation
positive regulation of interleukin-4 production
mammary gland epithelial cell proliferation
response to endoplasmic reticulum stress
T-helper 1 cell activation
negative regulation of T cell proliferation
defense response to bacterium
negative regulation of neuron apoptotic process
regulation of interleukin-6 biosynthetic process
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
brown fat cell differentiation
mammary gland epithelial cell differentiation
regulation of transcription involved in cell fate commitment
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to interleukin-1
cellular response to organic cyclic compound
hepatocyte proliferation
liver regeneration
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
