Invitrogen

Phospho-C2orf33 (Ser172, Ser146) Polyclonal Antibody

Phospho-C2orf33 (Ser172, Ser146) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Phospho-C2orf33 (Ser172, Ser146) Antibody (PA5-104614) in IHC (P)

Immunohistochemistry analysis of Phospho-C2orf33 (Ser172, Ser146) in human esophageal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-C2orf33 (Ser172, Ser146) polyclonal antibody (Product # PA5-104614) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.

Phospho-C2orf33 (Ser172, Ser146) Antibody in Western Blot (WB)

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产品信息

PA5-104614

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human MFF(Accession Q9GZY8), corresponding to amino acid residues around phosphorylated Ser172.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2816089

产品详细信息

Antibody detects endogenous levels of MFF only when phosphorylated at Ser172/146.

靶标信息

Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. [Uniprot]

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye.

Investigative ophthalmology & visual science

Peng F,Jiang D,Xu W,Sun Y,Zha Z,Tan X,Yu J,Pan C,Zheng Q,Chen W

PA5-104614 was used in Immunohistochemistry (Paraffin), Western Blot to assess the role of mitochondrial morphology and adenosine monophosphate-activated protein kinase (AMPK)/mitochondrial fission factor (MFF) in dry eye and the underlying mechanisms.

Tue Nov 01 00:00:00 UTC 2022

Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis.

JCI insight

Marek-Iannucci S,Ozdemir AB,Moreira D,Gomez AC,Lane M,Porritt RA,Lee Y,Shimada K,Abe M,Stotland A,Zemmour D,Parker S,Sanchez-Lopez E,Van Eyk J,Gottlieb RA,Fishbein MC,Karin M,Crother TR,Rivas MN,Arditi M

PA5-104614 was used in Western Blot to demonstrate that impaired autophagy/mitophagy and ROS-dependent damage exacerbate the development of murine KD vasculitis.

Wed Sep 22 00:00:00 UTC 2021

Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis.

JCI insight

PA5-104614 was used in Western Blot to demonstrate that impaired autophagy/mitophagy and ROS-dependent damage exacerbate the development of murine KD vasculitis.