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产品信息
PA5-36027
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide derived from human DNAM 1 around the phosphorylation site of Serine 329
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
15mM sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2553331
产品详细信息
This antibody detects endogenous protein at a molecular weight of 38 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion glycoprotein; CD226; CD226 antigen; DNAM 1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; Platelet and T-cell activation antigen 1; T lineage-specific activation antigen 1 antigen
基因别名: BC051526; CD226; DNAM-1; DNAM1; PTA1; TLiSA1
UniProt ID: (Human) Q15762, (Mouse) Q8K4F0
Entrez Gene ID: (Human) 10666, (Mouse) 225825
cytokine production
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
positive regulation of immunoglobulin mediated immune response
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
cell recognition
positive regulation of mast cell activation
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
positive regulation of Fc receptor mediated stimulatory signaling pathway
