Invitrogen

Phospho-CDK1/CDK2 (Thr14) Polyclonal Antibody

产品信息

PA5-67509

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthesized peptide derived from human CDK1/CDK2 around the phosphorylation site of Thr14.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2691675

产品详细信息

Predicted to react with Mouse and Rat samples.

靶标信息

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: cdc2-related protein kinase; CDK1; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; Cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; Cell division protein kinase 1; Cell division protein kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 1; Cyclin-dependent kinase 2; p33 protein kinase; p34 protein kinase

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基因别名: A630093N05Rik; CDC2; CDC28A; Cdc2a; CDK1; CDK2; CDKN1; CDKN2; p33(CDK2); p34; P34CDC2

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UniProt ID: (Human) P06493, (Human) P24941, (Rat) P39951, (Mouse) P11440, (Mouse) P97377

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Entrez Gene ID: (Human) 983, (Human) 1017, (Rat) 54237, (Mouse) 12534, (Rat) 362817, (Mouse) 12566

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protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity cyclin binding Hsp70 protein binding histone kinase activity kinase activity protein complex binding metal ion binding nucleotide binding transferase activity transferase activity, transferring phosphorus-containing groups non-receptor serine/threonine protein kinase

参与通路

G1/S transition of mitotic cell cycle regulation of transcription involved in G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle activation of MAPK activity microtubule cytoskeleton organization DNA replication DNA repair protein complex assembly apoptotic process DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest mitotic nuclear division mitotic nuclear envelope disassembly mitotic G2 DNA damage checkpoint centrosome cycle pronuclear fusion cell aging response to toxic substance positive regulation of gene expression regulation of Schwann cell differentiation response to organic cyclic compound response to amine response to activity cell migration histone phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation chromosome condensation epithelial cell differentiation organ regeneration anaphase-promoting complex-dependent catabolic process positive regulation of protein import into nucleus, translocation protein localization to kinetochore response to drug protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process response to ethanol positive regulation of DNA replication positive regulation of mitotic cell cycle regulation of embryonic development response to cadmium ion response to copper ion response to axon injury cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle ventricular cardiac muscle cell development positive regulation of cardiac muscle cell proliferation cellular response to hydrogen peroxide Golgi disassembly positive regulation of protein localization to nucleus lens development in camera-type eye potassium ion transport centriole replication meiotic nuclear division Ras protein signal transduction positive regulation of cell proliferation mitotic G1 DNA damage checkpoint positive regulation of DNA-dependent DNA replication initiation response to estradiol cellular response to insulin stimulus positive regulation of transcription, DNA-templated centrosome duplication response to cAMP response to electrical stimulus regulation of gene silencing cellular response to nitric oxide regulation of signal transduction by p53 class mediator mitotic cell cycle protein phosphorylation response to organonitrogen compound response to hydrogen peroxide cell cycle phosphorylation meiotic cell cycle regulation of cell cycle cellular response to DNA damage stimulus