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Phospho-CUX1 (Ser1237) Antibody (PA5-105988) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-CUX1 (Ser1237) in human lung cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-CUX1 (Ser1237) polyclonal antibody (Product # PA5-105988) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105988
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CUX1(Accession P39880), corresponding to amino acid residues around phosphorylated Ser1237.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2817387
产品详细信息
Antibody detects endogenous levels of CUTL1 only when phosphorylated at Ser1237.
靶标信息
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CCAAT displacement protein; CDP; CDP/Cux p200; CDP2; cut homolog; cut-like 1; cut-like homeobox 1; Cux/CDP homeoprotein; golgi integral membrane protein 6; Homeobox protein cut-like 1; Homeobox protein cux-1; Protein CASP; putative protein product of Nbla10317
基因别名: CASP; CDP; CDP/Cut; CDP1; Clox; COY1; CUTL1; CUX; Cux-1; Cux/CDP; CUX1; GOLIM6; Kiaa4047; Nbla10317; p100; p110; p200; p75
UniProt ID: (Human) P39880, (Mouse) P53564
Entrez Gene ID: (Human) 1523, (Rat) 116639, (Mouse) 13047
RNA polymerase II regulatory region sequence-specific DNA binding
protein tyrosine kinase activity
protein binding, bridging
sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
chromatin binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
retrograde transport, vesicle recycling within Golgi
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
peptidyl-tyrosine phosphorylation
positive regulation of dendrite morphogenesis
kidney development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
intra-Golgi vesicle-mediated transport
lung development
auditory receptor cell differentiation
positive regulation of transcription from RNA polymerase II promoter
transport
