Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
Phospho-Cdc5L (Tyr232) Antibody (PA5-105338) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-Cdc5L (Tyr232) in human kidney cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-Cdc5L (Tyr232) polyclonal antibody (Product # PA5-105338) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105338
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CDC5L(Accession Q99459), corresponding to amino acid residues around phosphorylated Tyr232.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816766
产品详细信息
Antibody detects endogenous levels of CDC5L only when phosphorylated at Tyr232.
靶标信息
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CDC5 cell division cycle 5-like; Cdc5-like protein; Cdc5-related protein; Cell division cycle 5-like protein; cell division cycle 5-related protein; dJ319D22.1 (CDC5-like protein); hCDC5; Pombe Cdc5-related protein
基因别名: 1200002I02Rik; AA408004; CDC5; CDC5-LIKE; CDC5L; CEF1; dJ319D22.1; KIAA0432; PCDC5RP
UniProt ID: (Human) Q99459, (Rat) O08837, (Mouse) Q6A068
Entrez Gene ID: (Human) 988, (Rat) 85434, (Mouse) 71702
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor recruiting
transcription corepressor binding
DNA binding
protein binding
protein phosphatase 1 binding
protein kinase binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
WD40-repeat domain binding
chromatin binding
protein domain specific binding
RNA binding
G2/M transition of mitotic cell cycle
DNA repair
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
RNA splicing
signal transduction involved in DNA damage checkpoint
mitotic cell cycle
mRNA splicing, via spliceosome
regulation of transcription from RNA polymerase II promoter
cell differentiation
cellular response to fibroblast growth factor stimulus
cellular response to interleukin-2
cellular response to wortmannin
cellular response to nerve growth factor stimulus
cellular response to prolactin
cellular response to DNA damage stimulus
cell cycle
