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Phospho-Desmoplakin (Ser165, Ser166) Antibody (PA5-105152) in IHC (P)
Immunohistochemistry analysis of Phospho-Desmoplakin (Ser165, Ser166) in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-Desmoplakin (Ser165, Ser166) polyclonal antibody (Product # PA5-105152) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody... View More
产品信息
PA5-105152
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DSP(Accession P15924), corresponding to amino acid residues around phosphorylated Ser166.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816625
产品详细信息
Antibody detects endogenous levels of Desmoplakin only when phosphorylated at Ser165/166.
靶标信息
Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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