Invitrogen

Phospho-ETS2 (Thr72) Polyclonal Antibody

Phospho-ETS2 (Thr72) Antibody in Immunocytochemistry (ICC/IF)

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Phospho-ETS2 (Thr72) Antibody (44-1105G) in ICC/IF

Immunofluorescence analysis of Phospho-ETS2 pThr72 was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton™ X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. The cells were labeled with Phospho-ETS2 pThr72 Rabbit Polyclonal Antibody (Product # 44-1105G)at 1:250 dilution in 1% BSA and incubated f... View More

Phospho-ETS2 (Thr72) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Phospho-ETS2 (Thr72) Antibody in Western Blot (WB)

Phospho-ETS2 (Thr72) Antibody in ChIP Assay (ChIP)

Phospho-ETS2 (Thr72) Antibody in Immunohistochemistry (IHC)

Product Image Gallery

产品信息

44-1105G

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看4篇已发表文章 4篇已发表文章

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:10-1:50

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

1:250

染色质免疫沉淀实验 (ChIP)

1-5 µg

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human ETS2 that contains threonine 72.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Affinity chromatography

保存液

Dulbecco's PBS, pH 7.3, with 1mg/mL BSA

内含物

0.05% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2533575

靶标信息

ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells.

International journal of molecular sciences

Sheng K,Wu Y,Lin H,Fang M,Xue C,Lin X,Lin X

44-1105G was used in Western Blotting to define a detailed molecular profile of how Siglec-15 is transcriptionally regulated which may offer significant opportunity for therapeutic intervention on HCC immunotherapy.

Mon Jan 02 00:00:00 UTC 2023

Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy.

Circulation

Luo Y,Jiang N,May HI,Luo X,Ferdous A,Schiattarella GG,Chen G,Li Q,Li C,Rothermel BA,Jiang D,Lavandero S,Gillette TG,Hill JA

Published figure using Phospho-ETS2 (Thr72) polyclonal antibody (Product # 44-1105G) in Western Blot

Tue Jul 06 00:00:00 UTC 2021

EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways.

International journal of biological sciences

Yang L,Zhu Y,Kong D,Gong J,Yu W,Liang Y,Nie Y,Teng CB

Published figure using Phospho-ETS2 (Thr72) polyclonal antibody (Product # 44-1105G) in Western Blot

Mon Jul 06 00:00:00 UTC 2020

Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.

Cell

Ge Y,Gomez NC,Adam RC,Nikolova M,Yang H,Verma A,Lu CP,Polak L,Yuan S,Elemento O,Fuchs E

441105G was used in immunohistochemistry to elucidate how cancers are distinguished from wounds

Thu May 04 00:00:00 UTC 2017

ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas.

eLife

Yang H,Schramek D,Adam RC,Keyes BE,Wang P,Zheng D,Fuchs E

44-1105G was used in immunohistochemistry - paraffin section to study chromatin dynamics and malignancy in squamous cell carcinomas driven by ETS family transcriptional regulators

Sat Nov 21 00:00:00 UTC 2015

Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion.

The EMBO journal

Pickard A,Cichon AC,Barry A,Kieran D,Patel D,Hamilton P,Salto-Tellez M,James J,McCance DJ

44-1105G was used in immunohistochemistry - paraffin section and western blot to study the mechanism by which inactivation of stromal fibroblast retinoblastoma protein promotes invasion of epithelial cells.

Tue May 29 00:00:00 UTC 2012

Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion.

The EMBO journal

Pickard A,Cichon AC,Barry A,Kieran D,Patel D,Hamilton P,Salto-Tellez M,James J,McCance DJ

Tue May 29 00:00:00 UTC 2012

Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion.

The EMBO journal

Pickard A,Cichon AC,Barry A,Kieran D,Patel D,Hamilton P,Salto-Tellez M,James J,McCance DJ

Tue May 29 00:00:00 UTC 2012

RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.

FEBS letters

Flavin P,Redmond A,McBryan J,Cocchiglia S,Tibbitts P,Fahy-Browne P,Kay E,Treumann A,Perrem K,McIlroy M,Hill AD,Young LS

Thu Aug 04 00:00:00 UTC 2011

RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.

FEBS letters

Flavin P,Redmond A,McBryan J,Cocchiglia S,Tibbitts P,Fahy-Browne P,Kay E,Treumann A,Perrem K,McIlroy M,Hill AD,Young LS

Thu Aug 04 00:00:00 UTC 2011

生物信息学

蛋白别名: oncogene ETS-2; Protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2

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基因别名: AU022856; Ets-2; ETS2; ETS2IT1

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UniProt ID: (Human) P15036, (Mouse) P15037

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Entrez Gene ID: (Human) 2114, (Mouse) 23872

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding glucocorticoid receptor binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding winged helix/forkhead transcription factor

参与通路

negative regulation of transcription from RNA polymerase II promoter skeletal system development ectodermal cell fate commitment transcription, DNA-templated mesoderm development cell differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter primitive streak formation regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter

Phospho-ETS2 (Thr72) Polyclonal Antibody

Phospho-ETS2 (Thr72) Antibody (44-1105G) in ICC/IF

产品信息

44-1105G

免疫印迹 (WB)

免疫组化 (IHC)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

染色质免疫沉淀实验 (ChIP)

其他PubMed (Misc)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

纯化类型

保存液

内含物

保存条件

运输条件

RRID

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

Phospho-ETS2 (Thr72) Polyclonal Antibody

Phospho-ETS2 (Thr72) Antibody (44-1105G) in ICC/IF

产品信息

44-1105G

免疫印迹 (WB)

免疫组化 (IHC)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

染色质免疫沉淀 实验 (ChIP)

其他PubMed (Misc)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

纯化类型

保存液

内含物

保存条件

运输条件

RRID

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

染色质免疫沉淀实验 (ChIP)