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Invitrogen
Phospho-EphA3/EphA4/EphA5 (Tyr779, Tyr833) Polyclonal Antibody
FIGURE: 1 / 1
Phospho-EphA3/EphA4/EphA5 (Tyr779, Tyr833) Antibody (PA5-37813) in IHC (P)
Immunohistochemical analysis of Phospho-EphA3/EphA4/EphA5 (Tyr779, Tyr833) in paraffin-embedded Human brain tissue using Phospho-EphA3/EphA4/EphA5 (Tyr779, Tyr833) Polyclonal Antibody (Product # PA5-37813) (left) or the same antibody preincubated with blocking peptide (right).
Product Details
PA5-37813
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y(p)-T-T)/(Q-D-V(p)-I-K) derived from Human EPHA3/4/5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2554421
Product Specific Information
A suggested positive control for IHC is human brain tissue.
Target Information
These proteins belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-specific kinase; EHK-1; EK4; EK7; EK8; EPH homology kinase 1; EPH-like kinase 4; EPH-like kinase 7; EPH-like kinase 8; Eph-like tyrosine kinase 1; Ephrin type-A receptor 3; Ephrin type-A receptor 4; Ephrin type-A receptor 5; H TYRO4; HEK; Human embryo kinase; human embryo kinase 1; receptor protein-tyrosine kinase HEK7; receptor protein-tyrosine kinase HEK8; testicular tissue protein Li 64; TYRO1 protein tyrosine kinase; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor EHK-1; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase TYRO4
Gene Aliases: BSK; CEK7; EHK-1; EHK1; EK4; EK7; EPHA3; EPHA4; EPHA5; ETK; ETK1; HEK; HEK4; HEK7; HEK8; SEK; TYRO1; TYRO4
UniProt ID: (Human) P29320, (Human) P54764, (Human) P54756
Entrez Gene ID: (Human) 2042, (Human) 2043, (Human) 2044
cell adhesion
regulation of epithelial to mesenchymal transition
positive regulation of neuron projection development
cell migration
peptidyl-tyrosine phosphorylation
regulation of actin cytoskeleton organization
regulation of GTPase activity
ephrin receptor signaling pathway
regulation of focal adhesion assembly
regulation of microtubule cytoskeleton organization
cellular response to retinoic acid
fasciculation of sensory neuron axon
fasciculation of motor neuron axon
adult walking behavior
motor neuron axon guidance
glial cell migration
corticospinal tract morphogenesis
positive regulation of JUN kinase activity
protein autophosphorylation
negative regulation of axon regeneration
regulation of astrocyte differentiation
regulation of axonogenesis
positive regulation of dendrite morphogenesis
regulation of dendritic spine morphogenesis
nephric duct morphogenesis
positive regulation of Rho guanyl-nucleotide exchange factor activity
axon guidance
cAMP-mediated signaling
hippocampus development
positive regulation of CREB transcription factor activity
neuron development
regulation of insulin secretion involved in cellular response to glucose stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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