Invitrogen

Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774) Polyclonal Antibody

Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774) Antibody (PA5-105950) in IHC (P)

Immunohistochemistry analysis of paraffin-embedded Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774) in human liver cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774) polyclonal antibody (Product # PA5-105950) using a dilution of 1:200 (1.5 hr, 22°C), follow... View More

Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774) Antibody in Western Blot (WB)

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产品信息

PA5-105950

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human EPHB1(Accession P54762), corresponding to amino acid residues around phosphorylated Tyr778.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2817349

产品详细信息

Antibody detects endogenous levels of EPH B1/3/4 only when phosphorylated at Tyr778/792/774.

靶标信息

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Developmental kinase 2; Developmental kinase 5; EK2; EK6; ELK; ELK-related protein tyrosine kinase; Embryonic kinase 2; Eph receptor B2 (ELK-related protein tyrosine kinase); EPH receptor B4; EPH tyrosine kinase 2; EPH-like kinase 2; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ephrin receptor EphB4; Ephrin type-B receptor 1; Ephrin type-B receptor 3; Ephrin type-B receptor 4; Hepatoma transmembrane kinase; human embryo kinase 2; mDK-2; mDK-5; NET; Neuronally-expressed EPH-related tyrosine kinase; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyrosine kinase MYK-1; Tyrosine-protein kinase receptor EPH-2; tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO11; Tyrosine-protein kinase TYRO6

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基因别名: 9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; Cek10; Cek6; EK2; ELK; Elkh; ENSMUSG00000074119; EPHB1; Ephb2; EPHB3; EPHB4; EPHT2; Epth2; Erk; ETK2; HEK2; HEK6; HTK; MDK2; MDK5; MYK1; NET; Sek4; TYRO11; TYRO6