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Phospho-Ephrin B1/B2/B3 (Tyr324/311/318) Antibody (PA5-37810) in IHC (P)
Immunohistochemical analysis of Phospho-Ephrin B1/B2/B3 (Tyr324) in paraffin-embedded Human brain tissue using Phospho-Ephrin B1/B2/B3 (Tyr324) Polyclonal Antibody (Product # PA5-37810) (left) or the same antibody preincubated with blocking peptide (right).
产品信息
PA5-37810
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide sequence around phosphorylation site of tyrosine 324/311/318 (G-D-Y(p)-G-H) derived from Human Ephrin B1/B2/B3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2554418
产品详细信息
A suggested positive control for Western blot is K562 cells; suggested positive control for IHC is human brain tissue.
靶标信息
Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EFL-3; ELK ligand; ELK-L; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; Ephrin-B1; Ephrin-B2; Ephrin-B3; HTK ligand; HTK-L; LERK-2; LERK-5; LERK-8; ligand of eph-related kinase 5
基因别名: CFND; CFNS; EFB1; EFL3; EFL6; EFNB1; EFNB2; EFNB3; Elk-L; EPLG2; EPLG5; EPLG8; Htk-L; HTKL; LERK2; LERK5; LERK8
UniProt ID: (Human) P98172, (Human) P52799, (Human) Q15768
Entrez Gene ID: (Human) 1947, (Human) 1948, (Human) 1949
neural crest cell migration
cell adhesion
cell-cell signaling
axon guidance
embryonic pattern specification
T cell costimulation
positive regulation of T cell proliferation
ephrin receptor signaling pathway
lymph vessel development
cell migration involved in sprouting angiogenesis
anatomical structure morphogenesis
organ morphogenesis
negative regulation of keratinocyte proliferation
viral entry into host cell
regulation of chemotaxis
nephric duct morphogenesis
positive regulation of cardiac muscle cell differentiation
nervous system development
adult walking behavior
axon choice point recognition
