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Phospho-FANCA (Ser1449) Antibody (PA5-105387) in ICC/IF
Immunofluorescent analysis of Phospho-FANCA (Ser1449) in HeLa cells(4h of LPS treatment). Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Phospho-FANCA (Ser1449) polyclonal antibody (Product # PA5-105387) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor ... View More
产品信息
PA5-105387
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FANCA(Accession O15360), corresponding to amino acid residues around phosphorylated Ser1449.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816815
产品详细信息
Antibody detects endogenous levels of FANCA only when phosphorylated at Ser1449.
靶标信息
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fanconi anemia group A protein; Fanconi anemia group A protein homolog; Fanconi anemia, complementation group A; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA
基因别名: AW208693; FA; FA-H; FA1; FAA; FACA; FAH; FANCA; FANCH
UniProt ID: (Human) O15360, (Mouse) Q9JL70
Entrez Gene ID: (Human) 2175, (Rat) 361435, (Mouse) 14087
