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Phospho-HSPH1 (Ser809) Antibody (PA5-106182) in WB
Western blot analysis of Phospho-HSPH1 (Ser809) in extracts from RAW264.7 cells (LPS 4h treatment). Samples were incubated with Phospho-HSPH1 (Ser809) polyclonal antibody (Product # PA5-106182). The lane on the left was treated with blocking peptide. Observed bands: 120 kDa.
产品信息
PA5-106182
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HSPH1(Accession Q92598), corresponding to amino acid residues around phosphorylated Ser809.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2817580
产品详细信息
Antibody detects endogenous levels of HSP105 only when phosphorylated at Ser809.
靶标信息
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 42 degrees C-HSP; Antigen NY-CO-25; heat shock 105kD alpha; heat shock 105kD beta; heat shock 105kDa; heat shock 105kDa/110kDa protein 1; Heat shock 110 kDa protein; Heat shock protein; Heat shock protein 105 kDa; heat shock protein 110; Heat shock protein family H member 1; heat shock protein, 105 kDa; Heat shock-related 100 kDa protein E7I; HSP; HSP-E7I; HSP105 42 C-HSP; NY CO 25
基因别名: 105kDa; AI790491; hsp-E7I; HSP105; HSP105A; HSP105B; HSP110; hsp110/105; HSPH1; KIAA0201; NY-CO-25
UniProt ID: (Human) Q92598, (Mouse) Q61699, (Rat) Q66HA8
Entrez Gene ID: (Human) 10808, (Mouse) 15505, (Rat) 288444
response to unfolded protein
negative regulation of neuron apoptotic process
positive regulation of MHC class I biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
chaperone mediated protein folding requiring cofactor
positive regulation of NK T cell activation
positive regulation of protein tyrosine kinase activity
regulation of microtubule cytoskeleton organization
negative regulation of establishment of protein localization to mitochondrion
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
negative regulation of p38MAPK cascade
negative regulation of apoptotic signaling pathway
receptor-mediated endocytosis
regulation of cellular response to heat
