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Phospho-JNK1/JNK2/JNK3 (Tyr185) Antibody (PA5-104907) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-JNK1/JNK2/JNK3 (Tyr185) in human liver cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-JNK1/JNK2/JNK3 (Tyr185) polyclonal antibody (Product # PA5-104907) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-104907
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MAPK8(Accession P45983), corresponding to amino acid residues around phosphorylated Tyr185.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816380
产品详细信息
Antibody detects endogenous levels of JNK1/2/3 only when phosphorylated at Tyrosine 185.
靶标信息
C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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