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Phospho-KCC2 (Thr1007) Antibody (PA5-95677) in WB
Western blot of KCC2 in rat hippocampal lysate showing specific labeling of a band at ~135 kDa corresponding to Phospho-KCC2 (Thr1007) polyclonal antibody (Product # PA5-95677) in the first lane (-). Phosphospecificity is shown in the second lane (+) where immunolabeling is completely eliminated by blot treatment with lambda phosphatase (1,200 units for 30 min).
产品信息
PA5-95677
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr1007 of rat KCC2 conjugated to KLH
偶联物
形式
Liquid
浓度
~0.25 mg/mL
纯化类型
Antigen Affinity Chromatography
保存液
10mM HEPES, pH 7.5, with 100µg/mL BSA, 50% glycerol, 0.15M NaCl
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2807479
产品详细信息
Antigen Affinity Purified from Pooled Serum
靶标信息
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Electroneutral potassium-chloride cotransporter 2; Furosemide-sensitive K-Cl cotransporter; K-Cl cotransporter 2; KCC 2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; mKCC2; Neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; Solute carrier family 12 member 5; solute carrier family 12, member 5
基因别名: KCC2; Kiaa1176; mKIAA1176; Slc12a5
UniProt ID: (Mouse) A2A5L0, (Rat) Q63633
Entrez Gene ID: (Mouse) 57138, (Rat) 171373
transport
ion transport
potassium ion transport
chloride transport
chemical synaptic transmission
learning
organic cation transport
ammonium transport
multicellular organism growth
thermosensory behavior
response to drug
intracellular pH reduction
transmembrane transport
ammonium transmembrane transport
cation transmembrane transport
chloride transmembrane transport
