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Phospho-KV2.1 (Ser805) Antibody (PA5-37586) in IHC (P)
Immunohistochemical analysis of Phospho-KV2.1 (Ser805) in paraffin-embedded human Squamous cell carcinoma of lung. 1)Phospho-KV2.1 (Ser805) Polyclonal Antibody (Product # PA5-37586) was diluted at 1:200 (4° overnight). 2) Tris-EDTA,pH9.0 was used for antigen retrieval. 3) Secondary antibody was diluted at 1:200 (room temperature, 45 min).
Product Details
PA5-37586
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around phosphorylation site of serine805(P-T-S(p)-P-K) derived from Human Kv2.1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2554194
Product Specific Information
A suggested positive control for Western blot is K562 cells.
Target Information
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Delayed rectifier potassium channel 1; DRK1; KCB1; Potassium voltage-gated channel subfamily B member 1; potassium voltage-gated channel, Shab-related subfamily, member 1; Voltage-gated potassium channel subunit Kv2.1
Gene Aliases: DRK1; KCNB1; Kv2.1
UniProt ID: (Human) Q14721
Entrez Gene ID: (Human) 3745
action potential
vesicle docking involved in exocytosis
glutamate receptor signaling pathway
positive regulation of norepinephrine secretion
cellular response to nutrient levels
positive regulation of catecholamine secretion
regulation of ion transmembrane transport
glucose homeostasis
positive regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
regulation of insulin secretion
protein homooligomerization
cellular response to glucose stimulus
potassium ion transmembrane transport
protein targeting to plasma membrane
positive regulation of protein targeting to membrane
regulation of action potential
positive regulation of long term synaptic depression
regulation of motor neuron apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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