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A suggested positive control for IHC is human brain tissue.
MLK is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: mitogen activated protein kinase kinase kinase 9; Mitogen-activated protein kinase kinase kinase 10; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); Mixed lineage kinase 2; MKN28 derived nonreceptor_type; MKN28 derived nonreceptor_type serine/threonine kinase; MKN28 kinase; Protein kinase MST; serine/threonine kinase
基因别名: BC028668; BC046514; E130314H24Rik; MAP3K10; MAP3K9; MEKK10; MEKK9; MLK1; MLK2; MST; PRKE1
UniProt ID: (Human) Q02779, (Human) P80192, (Mouse) Q66L42, (Mouse) Q3U1V8
Entrez Gene ID: (Human) 4294, (Human) 4293, (Mouse) 269881, (Mouse) 338372