Invitrogen

Phospho-MLKL (Ser358) Polyclonal Antibody

Phospho-MLKL (Ser358) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Phospho-MLKL (Ser358) Antibody (PA5-105678) in IHC (P)

Immunohistochemistry analysis of paraffin-embedded Phospho-MLKL (Ser358) in human gastric cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-MLKL (Ser358) polyclonal antibody (Product # PA5-105678) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.

Phospho-MLKL (Ser358) Antibody in Western Blot (WB)

Phospho-MLKL (Ser358) Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-105678

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看2篇已发表文章 2篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human MLKL(Accession Q8NB16), corresponding to amino acid residues around phosphorylated Ser358.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2817106

产品详细信息

Antibody detects endogenous levels of MLKL only when phosphorylated at Ser358.

靶标信息

The protein kinase domain is predicted to be catalytically inactive. Molecular function: protein binding. There are two isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect.

Frontiers in pharmacology

Guo X,Li R,Cui J,Hu C,Yu H,Ren L,Cheng Y,Jiang J,Ding X,Wang L

Published figure using Phospho-MLKL (Ser358) polyclonal antibody (Product # PA5-105678) in Immunohistochemistry

Wed Sep 13 00:00:00 UTC 2023

Serum amyloid A3 is required for caerulein-induced acute pancreatitis through induction of RIP3-dependent necroptosis.

Immunology and cell biology

Yang X,Li R,Xu L,Qian F,Sun L

PA5-105678 was used in Immunohistochemistry (Paraffin), Western Blot to evaluate the relationship of serum amyloid A and acute pancreatitis in mice.

Fri Jan 01 00:00:00 UTC 2021

Serum amyloid A3 is required for caerulein-induced acute pancreatitis through induction of RIP3-dependent necroptosis.

Immunology and cell biology

Yang X,Li R,Xu L,Qian F,Sun L

PA5-105678 was used in Immunohistochemistry (Paraffin), Western Blot to evaluate the relationship of serum amyloid A and acute pancreatitis in mice.

Fri Jan 01 00:00:00 UTC 2021

Cell death inhibitors protect against brain damage caused by cardiac ischemia/reperfusion injury.

Cell death discovery

Liao S,Apaijai N,Luo Y,Wu J,Chunchai T,Singhanat K,Arunsak B,Benjanuwattra J,Chattipakorn N,Chattipakorn SC

PA5-105678 was used in Immunohistochemistry (Paraffin), Western Blot to show that cell death inhibitors prevented hippocampal dendritic spine loss caused by cardiac I/R injury through different mechanisms.