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Phospho-PPIG (Ser376) Antibody (PA5-105205) in ICC/IF
Immunocytochemistry analysis of Phospho-PPIG (Ser376) in Hela cells (4h of LPS treatment). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-PPIG (Ser376) polyclonal antibody (Product # PA5-105205) 1:200 and mouse anti-beta tubulin antibody (1:200) for 1 hour at 37°C. An AlexaFluor594 conjugated goat ... View More
产品信息
PA5-105205
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PPIG(Accession Q13427), corresponding to amino acid residues around phosphorylated Ser376.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816678
产品详细信息
Antibody detects endogenous levels of PPIG only when phosphorylated at Ser376.
靶标信息
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; Matrin cyclophilin; matrin cyclophilin (matrin-cyp); Matrin-cyp; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidyl-prolyl isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); peptidylprolyl isomerase G; peptidylprolyl isomerase G (cyclophilin G); PPIase G; Rotamase G; SR-cyclophilin; SR-cyp; SR-related CTD-associated factor 10
基因别名: AU019516; AU022200; B230312B02Rik; CARS-Cyp; CYP; PPIG; SCAF10; SRCyp
UniProt ID: (Human) Q13427, (Rat) O55035, (Mouse) A2AR02
Entrez Gene ID: (Human) 9360, (Rat) 83624, (Mouse) 228005
