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Phospho-RGS19 (Ser151) Antibody (PA5-118694) in IHC (P)
Immunohistochemical analysis of Phospho-RGS19 (Ser151) in Mouse brain tissue using a Phospho-RGS19 (Ser151) polyclonal antibody (Product # PA5-118694). The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the seconda... View More
产品信息
PA5-118694
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RGS19(Accession P49795), corresponding to amino acid residues around phosphorylated Ser151.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903194
产品详细信息
Antibody detects endogenous levels of RGS19 only when phosphorylated at Ser151.
靶标信息
RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium/calmodulin-dependent protein kinase I; G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19
基因别名: 2610042F04Rik; AI324841; AW547781; Camki; GAIP; GNAI3IP; RGS19; RGSGAIP
UniProt ID: (Human) P49795, (Mouse) Q9CX84, (Rat) O70521
Entrez Gene ID: (Human) 10287, (Mouse) 56470, (Rat) 59293
regulation of transcription, DNA-templated
autophagy
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
cell death
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
positive regulation of GTPase activity
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
biological_process
regulation of G-protein coupled receptor protein signaling pathway
