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Phospho-SQSTM1 (Thr269, Ser272) Antibody (PA5-104657) in ICC/IF
Immunocytochemistry analysis of Phospho-SQSTM1 (Thr269, Ser272) in Heat-shock treated Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-SQSTM1 (Thr269, Ser272) polyclonal antibody (Product # PA5-104657) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated go... View More
产品信息
PA5-104657
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SQSTM1(Accession Q13501), corresponding to amino acid residues around phosphorylated Ser272.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816132
产品详细信息
Antibody detects endogenous levels of SQSTM1/p62 only when phosphorylated at Thr269/Ser272.
靶标信息
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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