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Phospho-SSH3 (Ser37) Antibody (PA5-104659) in ICC/IF
Immunocytochemistry analysis of Phospho-SSH3 (Ser37) in Heat-shock treated Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-SSH3 (Ser37) polyclonal antibody (Product # PA5-104659) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L... View More
产品信息
PA5-104659
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SSH3(Accession Q8TE77), corresponding to amino acid residues around phosphorylated Ser37.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816134
产品详细信息
Antibody detects endogenous levels of SSH3 only when phosphorylated at Ser37.
靶标信息
The ADF (actin-depolymerizing factor)/cofilin family is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hSSH-3L; Protein phosphatase Slingshot homolog 3; slingshot 3; slingshot homolog 3; slingshot-3L; slingshot-like 3; SSH-3L; SSH-like protein 3
基因别名: BC028922; mSSH-3L; SSH-3; SSH3; SSH3L
UniProt ID: (Human) Q8TE77, (Mouse) Q8K330, (Rat) Q5XIS1
Entrez Gene ID: (Human) 54961, (Mouse) 245857, (Rat) 365396
