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Phospho-Syndecan 4 (Ser179) Antibody (PA5-105801) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-Syndecan 4 (Ser179) in rat gastric tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-Syndecan 4 (Ser179) polyclonal antibody (Product # PA5-105801) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105801
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SDC4(Accession P31431), corresponding to amino acid residues around phosphorylated Ser179.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2817200
产品详细信息
Antibody detects endogenous levels of Syndecan 4 only when phosphorylated at Ser179.
靶标信息
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amphiglycan; MGC22217; ryudocan amphiglycan; Ryudocan core protein; Ryudocan/syndecan 4; SYND4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; Syndecan-4
基因别名: AA959608; AW108331; RATRYUDOCA; RYUDOCA; ryudocan; S4; SDC4; SYND4; syndecan-4
UniProt ID: (Human) P31431, (Rat) P34901, (Mouse) O35988
Entrez Gene ID: (Human) 6385, (Rat) 24771, (Mouse) 20971
retinoid metabolic process
ureteric bud development
neural tube closure
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
signal transduction
regulation of fibroblast migration
cell migration
glycosaminoglycan metabolic process
wound healing
positive regulation of protein kinase activity
positive regulation of stress fiber assembly
positive regulation of focal adhesion assembly
inner ear receptor stereocilium organization
positive regulation of exosomal secretion
positive regulation of extracellular exosome assembly
cell adhesion
cell-cell signaling
