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Phospho-delta Catenin (Tyr904) Antibody (PA5-118687) in IHC (P)
Immunohistochemical analysis of Phospho-delta Catenin (Tyr904) in Mouse colorectal tissue using a Phospho-delta Catenin (Tyr904) polyclonal antibody (Product # PA5-118687). The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody wa... View More
产品信息
PA5-118687
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CTNND1(Accession O60716), corresponding to amino acid residues around phosphorylated Tyr904.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903187
产品详细信息
Antibody detects endogenous levels of CTNND1 only when phosphorylated at Tyr904.
靶标信息
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin-associated protein), delta 1; Catenin delta-1; catenin src; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); p120-catenin
基因别名: AA409437; AU019353; CAS; Catns; CTNND; CTNND1; KIAA0384; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN
UniProt ID: (Human) O60716, (Mouse) P30999
Entrez Gene ID: (Human) 1500, (Mouse) 12388
transcription, DNA-templated
regulation of transcription, DNA-templated
cell adhesion
brain development
Wnt signaling pathway
single organismal cell-cell adhesion
adherens junction organization
negative regulation of canonical Wnt signaling pathway
morphogenesis of a polarized epithelium
salivary gland morphogenesis
keratinocyte differentiation
epithelial cell differentiation involved in salivary gland development
